Clinicopathologic and endoscopic features of early-stage colorectal serrated adenocarcinoma
نویسندگان
چکیده
منابع مشابه
Clinicopathologic and endoscopic features of early-stage colorectal serrated adenocarcinoma
BACKGROUND Serrated adenocarcinoma (SAC) is a distinct colorectal carcinoma variant that accounts for approximately 7.5% of all advanced colorectal carcinomas. While its prognosis is worse than conventional carcinoma, its early-stage clinicopathologic features are unclear. We therefore aimed to clarify the clinicopathologic and endoscopic characteristics of early-stage SACs. METHODS Forty con...
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OBJECTIVE Serrated adenocarcinoma (SAC), proposed as a new pathologic type, arises predominantly in the right side of the colon and has a poorer prognosis than conventional colorectal carcinoma. The prognosis of colorectal carcinoma is variable in Dukes' B, so the aim of this study was to determine whether or not SAC has a poor prognosis in Dukes' B. METHODS The study group comprised 64 patie...
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BACKGROUND We performed a retrospective study to assess the clinicopathological characters, molecular alterations and multigene mutation profiles in colorectal cancer patients with signet-ring cell component. METHODS Between November 2008 and January 2015, 61 consecutive primary colorectal carcinomas with signet-ring cell component were available for pathological confirmation. RAS/BRAF status...
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BACKGROUND/AIMS Serrated polyps have emerged as important evidence supporting the serrated polyp-neoplasia pathway in colorectal carcinogenesis, an alternate to the classical adenoma-carcinoma sequence. However, there is confusion over the diagnostic criteria for serrated polyps including traditional serrated adenoma (TSA) and sessile serrated adenoma (SSA). In addition, clinical and pathologic...
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ژورنال
عنوان ژورنال: BMC Gastroenterology
سال: 2017
ISSN: 1471-230X
DOI: 10.1186/s12876-017-0702-x